Advertisement

THE RELATIONSHIP BETWEEN TAU PET AND AGE ACROSS THE LIFESPAN

      The introduction of PET imaging with AV-1451 (flortaucipir) has provided a unique insight into the pathophysiology of Alzheimer Disease (AD). Prior work has consistently found elevated levels of flortaucipir binding in the lateral temporal lobes, precuneus, and lateral parietal regions in individuals with preclinical and clinical AD. It is unknown whether this tracer is sensitive to primary age-related increases in tau in the medial temporal lobe and whether off-target binding in the choroid plexus and basal ganglia vary as a function of age.
      To read this article in full you will need to make a payment
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'