Advertisement

OBSTRUCTIVE SLEEP APNEA, BRAIN BETA-AMYLOID MEASURES AND TIME-TO-PROGRESSION FROM MILD COGNITIVE IMPAIRMENT TO ALZHEIMER’S DISEASE

      Recent studies have demonstrated associations between Obstructive Sleep Apnea (OSA) and brain beta amyloid and cerebrospinal fluid Aβ-42 levels. Our objective was to evaluate the effect of OSA on time-to-progression from mild cognitive impairment (MCI) to Alzheimer’s dementia (AD) in amyloid positive versus amyloid negative elderly participants from the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort and to quantify the effect of OSA on the risk of progression as the biomarkers become increasingly abnormal
      To read this article in full you will need to make a payment
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'