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Recent studies have demonstrated associations between Obstructive Sleep Apnea (OSA)
and brain beta amyloid and cerebrospinal fluid Aβ-42 levels. Our objective was to
evaluate the effect of OSA on time-to-progression from mild cognitive impairment (MCI)
to Alzheimer’s dementia (AD) in amyloid positive versus amyloid negative elderly participants
from the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort and to quantify
the effect of OSA on the risk of progression as the biomarkers become increasingly
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