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Banner Alzheimer's Institute, Phoenix, AZ, USAUniversity of Arizona, Tucson, AZ, USAArizona State University, Tempe, AZ, USAArizona Alzheimer's Consortium, Phoenix, AZ, USATranslational Genomics Research Institute, Phoenix, AZ, USA
In this study, we used voxel-based morphometry (VBM) to characterize relationships
between florbetapir PET measurements of mean cortical amyloid-β (Ab) burden and MRI
measurements of regional gray matter volume in over a thousand persons from the AD
Neuroimaging Initiative (ADNI), including those who met clinical criteria for dementia
or mild cognitive impairment (MCI) due to AD and in cognitively unimpaired APOE4 carriers
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