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EFFECTIVE CONNECTIVITY WITHIN THE DEFAULT MODE NETWORK IN MILD COGNITIVE IMPAIRMENT AND ALZHEIMER'S DISEASE

      The default mode network (DMN) is well-recognized as being involved in memory and affected by dementia due to Alzheimer’s disease (AD), with differences in this network previously noted between healthy controls and AD patients. Previous studies of DMN effective connectivity in AD, such as used models of hemodynamic effective connectivity along with t-tests to compare connections between groups. Dynamic causal modeling (DCM) was used to explore neuronal effective connectivity differences between healthy controls and a group of mild cognitive impairment (MCI) and AD patients.
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