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DEFAULT MODE NETWORK CONNECTIVITY IN MCI SUBGROUPS ACCORDING TO AT(N) CLASSIFICATION COMPARED TO HEALTHY AGING

      Disruption in Default Mode Network (DMN) functional connectivity (FC) is commonly found in Alzheimer's Disease (AD), but studies in MCI have showed conflicting results (normal, hyper or hypoconnectivity) and one of the possible reasons may be the difference regarding AD pathophysiology status in MCI subjects. We compared DMN FC in MCI subjects considering the AT(N) classification and divided subjects in suspected non-Alzheimer’s pathophysiology (SNAP), AD continuum (A+) and normal AD biomarkers (N).
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