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Patients with mild cognitive impairment (MCI) with visual hallucinations, REM-sleep
behavior disorder, parkinsonism or fluctuations may have prodromal dementia with Lewy
bodies (DLB), but they often have overlapping Alzheimer’s disease-related pathology
as well. Identifying the imaging findings associated with prodromal DLB is necessary
for understanding the disease progression and predicting who will progress to probable
DLB in the near future. We investigated the distribution and magnitude of regional
brain atrophy rates in prodromal DLB. Using AV-1451 PET, we assessed the association
of tau-related pathology and atrophy rates.
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