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In conditions distinct from the frontotemporal lobar degenerations (FTLD), the transactive
response DNA-binding protein of 43 kDa (TDP-43) appears to follow a staging scheme
that involves first the amygdala, followed by the entorhinal cortex and hippocampus,
and then neocortical regions. In the present study, we aimed at providing a better
understanding of the link between TDP-43 staging and gray matter volume in a cohort
of non-FTLD subjects.
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